7 L Fermentation Course
In both classroom and labs at our Edinburgh based scale-up facility, our experienced team will cover the skills required to assess and up-scale cultures from shake flask to 7L bioreactor. This course includes an introduction to process design and consideration of a variety of parameters to optimise cell growth, as well as highlighting some common pitfalls of scale-up.
Course content typically includes:
Underlying cellular microbiology and media design
7 L vessel assembly and preparation
Loading and sterilisation of a vessel
Control of pH, DO, temperature and online optical density probe set-up
Design and preparation of inoculum train
Correct sterile sampling technique
Final end-point sampling and harvest
Disinfection vs. sterilisation - The discerning difference
Review of experimental data and process
Please contact our Facility manager to note interest.
Courses will be scheduled according to interest